In conjunction with audiometric testing, OAE testing can be completed to determine changes in the responses. Studies have found that exposure to noise can cause a decline in OAE responses. In a study, industrial workers who were exposed to 84.5 dBA of noise were compared to workers who were exposed to 53.2 dBA of noise by considering hearing thresholds and OAEs before and after 5 days of work. This study revealed that hearing thresholds and OAE results were significantly lower among the workers who were exposed to higher levels of noise.[12]

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Child development researcher, Lian Tong, analysed the results from a Haley and Stansbury experiment saying, "Parent responsiveness also facilitates cognitive, social, and emotional development and reduces negative emotions in infants."[30] That is, the amount of time that a parent or teacher is willing to spend teaching, listening to, playing with, and exploring with the child the more socially, emotionally, and educationally developed the child will become. Whether that child receives the majority of his or her care at a center or at its house, the biggest factor in deciding what will have the best effect on the child will be those willing to put in the time and effort it takes to properly develop a child's social, physical, and academic skills.
Legislation may mandate staffing ratios (for example, 6 weeks to 12 months, 1:4; 12 months to 18 months, 1:5; 18 months to 24 months, 1:9; etc.). The caregiver-to-child ratio is one factor indicative of quality of care. Ratios vary greatly by location and by daycare center. Potential consequences of a caregiver:child ratio which is too high could be very serious[citation needed]. However, many states allow a higher numbers of toddlers to caregivers and some centers do not comply consistently. For example, within the US: Pennsylvania, ages 1–3, 1 teacher to 5 children;[68] Missouri: age 2, 1 teacher to 8 children;[69] North Carolina: 1 teacher to 10 children.[67]

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Childcare infection is the spread of infection during childcare, typically because of contact among children in daycare or school.[36] This happens when groups of children meet in a childcare environment, and there is an individual with an infectious disease who may then spread it to the entire group. Commonly spread diseases include influenza-like illness and enteric illnesses, such as diarrhea among babies using diapers. Illnesses and diseases may also include ringworm, head lice, and hand, feet, mouth disease. It is uncertain how these diseases spread, but hand washing reduces some risk of transmission and increasing hygiene in other ways also reduces risk of infection.[37][38]
Plato, according to Elaine Hoffman Baruch, around 394 B.C., argued that a system of child care would free women to participate in society.[45] Among the early English authors to devote a book to child care in the modern sense was Elizabeth Dawbarn (The Rights of Infants, or... Nursing of Infants, 1805).[46] Day care, daycare,[47][48] child day care, or childcare is the care of a child during the day by a person other than the child's legal guardians, typically performed by someone outside the child's immediate family. Day care is typically an ongoing service during specific periods, such as the parents' time at work.
“Our daughter, Juliana, joined the TLE Aurora family at 8 weeks old and we could not be happier with our choice in a childcare facility. Ms. Bethany in the Infant A room is truly amazing! We are put at ease knowing that we have such a caring and loving teacher taking care of our daughter. She is truly dedicated to making sure Juliana progresses and has fun at the same time. Juliana always has a smile on her face when I drop her off in the morning and when I pick her up in the afternoon. We truly appreciate the staff at TLE Aurora for the way they have cared for our daughter as though she was family!” 

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The National Institute of Health released a study in March, 2007 after following a group of children through early childhood to the 6th grade.[89] The study found that the children who received a higher quality of childcare scored higher on 5th grade vocabulary tests than the children who had attended childcare of a lower quality. The study also reported that teachers found children from childcare to be "disobedient", fight more frequently, and more argumentative. The study reported the increases in both aggression and vocabulary were small. "The researchers emphasized that the children’s behavior was within the normal range and were not considered clinically disordered."